The following is a list of the world wide chain hotels which have hotels in Panama City. Please also note, all hotels in Panama are now non-smoking.
The Hotel Miramar Intercontinental, Panama
The Hotel Miramar Intercontinental on Av. Balboa y Fdco Boyd is a luxury hotel in Panama, on the waterfront overlooking the Pacific Ocean in the banking district. Great shopping is nearby as well as the Atlap Convention Center. The price for a single or double room is US $215 per night. All rooms have a balcony. The price includes a breakfast buffet. In total, there are 206 rooms and suites, telephone, mini bar, bathrobes, cable TV and satellite, internet, a business center and meeting rooms, local newspaper, room services, laundry, and gym, swimming pool, and health club. The health club offers sauna, whirlpool, tennis courts, and a Turkish bath. You can hire yachts, go fishing and find other available water sports at the private marina. Tennis courts are also available. For evening entertainment, there is the fifth floor lounge, Sparkles, with live music two nights a week. The Hotel Miramar Intercontinental also provides disabled traveller access.
Gourmet and international menus are available at the Bayview Restaurant which is open for breakfast, lunch and dinner. Snacks are available at Las Olas by the pool.
Hotel Marriott Panama

At Calle 52 y Ricardo Arias, Panama City, in the banking district, (12 miles from Tocumen Airport) you will find the Hotel Marriott Panama. It is ideal for business travellers because of its location in the banking district. A single and double room will cost you from U.S. $172. and a triple room goes for US $207 per night. The price of the room also includes a buffet breakfast. The hotel is made up of 396 rooms; there is a restaurant, a bar, a fitness center, cable TV, air conditioning, meeting rooms, laundry and an information desk. Excellent conference & meeting facilities are available in the business center and high-speed Internet. Also, be sure to visit the onsite gaming casino.
The Hotel Marriott Panama provides all the expected luxuries and comforts of the Marriott hotel chain world wide. There is a lobby bar and an American bar, the Marriott Café restaurant serving a la carte & buffet items. Once a week, a Panamanian buffet is served and on Friday evenings, a delicious seafood buffet is available.
Hotel Sheraton Panama
The Hotel Sheraton Panama on via Israel, Panama City offers 360 rooms, air conditioned, cable TV, telephone, laundry, gym, tennis court, a swimming pool, a spa, restaurants, bars, a night club, casino, meeting rooms, and an information desk for tourists.
Prices for the rooms begin at US $173 for a single room.
Hotel Crowne Plaza Panama
The Hotel Crowne Plaza Panama on the Av. Manuel Espinosa Batista in El Cangrejo district has 150 air conditioned rooms and suites, coffee makers, Internet, Fax, dining room, kitchenette in the suites, computers, internet access, and cable TV. Its restaurant called La Galeria serves fine cuisine. The bar "Memories" – is a sports bar serving international beverages. There is a nightclub, a fitness center, meeting rooms, laundry and a concierge. A single room starts at the price of US $146. This is an ideal hotel in Panama City for the business traveller because of its excellent location in the business district, El Cangrejo.
Courtyard by Marriott Plaza Real, Panama
The Courtyard by Marriott Plaza Real in the Multi Plaza Mall on the Punta Pacifica
has 150 rooms for its guests, Internet, Fax, dinning room, kitchenette, computers, coffee Maker, cable TV restaurant, bar, discoteque, gym, meeting rooms, laundry and a concierge and information desk to provide information to its guests. Prices for the rooms start at US $138 for a single to US $172 for a triple room. The price also includes a buffet breakfast.
Four Points Sheraton Panama

The Four Points Sheraton in Panama City on the Calle 43 Este in Marbella has 128 air conditioned rooms and suites from US $120 to US $138 offering such amenities as cable TV, telephone, laundry services. Price includes a breakfast buffet. Other amenities include a restaurant, bar, fitness center.
Hotel Plaza Paitilla Inn, Panama
Hotel Plaza Paitilla Inn situated on the Via Italia, Paitilla offers its guests rooms and suites from US $90 to US $148 including breakfast buffet. The 252 rooms and suites are air conditioned, with Cable TV, telephone, room service, a fitness center and information desk for its guests. There are several restaurants in the hotel, bars and a nightclub. Meeting and banquet facilities are available.
The Best Western Suites Las Huacas, Panama

As you can see, there are many international chain hotels in Panama City offered for business travellers and vacationers alike. The city of Panama is in a unique location, offering fabulous shopping, casinos, business and commerce, 85 international banks in the banking district, the Pacific Ocean, beach front views, magnificent skylines and the mountains in the background. If you are more interested in beach hotels Panama City, you can book your vacation at a resort such as the Royal Decameron Beach resort or the Playa Blanca Hotel and Resort. For those who want to explore nature and the rainforests of Panama, you could investigate the 5 star luxury Gamboa Rainforest Resort. Panama City offers so much to the business traveller or the vacationer alike.